Leeds, June 2026 – Axis Spine Technologies announces the publication of its clinical manuscript evaluating the company’s Axis Modular ALIF System.
The paper, titled “Radiographic Evaluation of a Modular Anterior Lumbar Interbody Fusion (ALIF) Cage: Subsidence and Segmental Lordosis”, has been published in Cureus and reports early multicenter clinical experience with the Axis Modular ALIF platform across four US centers and five experienced spine surgeons.
The retrospective cohort evaluated 23 patients (27 treated levels) and focused on radiographic subsidence and segmental lordosis outcomes following implantation of the modular device. Independent radiographic analysis was performed using validated AI-assisted FXA imaging software through an independent core laboratory.
A few key highlights from the publication:
- 23-patient multicenter retrospective cohort across four U.S. centers and five experienced spine surgeons
- No observed radiographic subsidence (>1mm threshold) in any evaluated level during follow-up
- Approximately 8° increase in segmental lordosis postoperatively, maintained through follow-up
- No reported implant-related intraoperative complications or revision surgeries during the study period
The manuscript also discusses the clinical rationale behind Axis’ modular, endplate-first insertion approach, including:
- Protection of vertebral endplates during insertion
- Reduction of insertional trauma
- Ability to independently address posterior height and lordotic correction
- Potential advantages in maintaining foramina height and sagittal alignment
“This publication represents an important early step in the company’s clinical evidence development pathway.” said Ivo Scheepens, VP Strategy at Axis Spine Technologies. “While additional clinical data and larger standardized patient cohorts will be important moving forward, we are pleased to see the early clinical experience with the Axis Modular ALIF platform now formally published.”
Axis states that the publication forms part of a broader program generating clinical evidence intended to further evaluate the company’s modular interbody technology platform across a variation of thoracolumbar applications.
The Axis Modular ALIF System received FDA 510(k) clearance in 2020 and is currently being utilized at selected clinical sites in the United States.
Click here to access the full publication.
About Axis Spine Technologies
Axis Spine Technologies is an early-commercial-stage spinal implant company focused on modular interbody technology. Its FDA 510(k)-cleared Axis Modular ALIF System provides surgeons with the ability to independently configure lordosis angle (up to 40°), foraminal height, coronal taper options (up to 20°), and patient anatomy-matching endplates—all selected intraoperatively after disc preparation when the anatomy is fully understood.
Supported by peer-reviewed biomechanical and early clinical evidence and protected by intellectual property spanning the thoracolumbar interbody space, Axis markets its differentiated modular ALIF technology. The system enables surgeons to construct implants in a variety of geometries to accommodate patients’ individual pathology and anatomical conditions within the cleared indications. The company is headquartered in Leeds, UK, with active commercial operations in the United States.
MEDIA CONTACT
Axis Spine Technologies
enquiries@axisspinetech.com
www.axisspinetech.com
