St. Albans, 7 May 2025 — A new peer-reviewed study published in Clinical Biomechanics (April 2025) reinforces the importance of implant design in preserving endplate integrity and achieving sagittal alignment in ALIF procedures. The research, conducted by the renowned research team in spine biomechanics at the Institute of Orthopaedic Research and Biomechanics in Ulm, Germany under the leadership of Professor Hans-Joachim Wilke, offers compelling insights into the clinical advantages of Modular Interbody Cages.
The study compared different ALIF implantation techniques using Modular and Monobloc cages in a controlled, in vitro setting. Key findings include:
- Modular Cages result in significantly fewer severe endplate defects during insertion.
- Greater segmental lordosis correction was achieved using Modular technique, without increasing the risk of endplate damage.
- Severe endplate fragmentation — which is associated with increased risk of subsidence — was less frequent with Modular Designs.
“These results support the clinical rationale behind Axis-ALIF’s Modular Design,” said Jon Arcos, Founder and CEO of Axis Spine Technologies. “Modular technology allows surgeons to insert implants with minimal force, match anatomy with patient customization and achieve 3D correction. This study combined with clinical evidence presented at the ISASS Annual Conference in Miami FL (April, 2025) further validates our commitment to Precision, Protection, and Performance.”
“Our research highlights that the choice of implant design and insertion technique directly affects the integrity of vertebral endplates,” said Prof. Hans-Joachim Wilke, senior author and Co-Director of the Institute of Orthopaedic Research and Biomechanics at University Hospital Ulm. “Modular insertion strategies showed promising results in limiting endplate damage while allowing for meaningful alignment correction.”
Axis-ALIF is a next-generation Modular Interbody Cage designed to support surgeons in restoring spinal alignment with a less traumatic, more adaptable approach — particularly in complex or multi-level degenerative cases where endplate integrity is critical.
For more information, or to access the full study, please contact:
enquiries@axisspinetech.com
or visit www.axisspinetech.com
About Axis Spine Technologies
Axis Spine Technologies is a medical device company focused on rethinking spinal implant design through Modular, Precision-Engineered Technologies. With a commitment to innovation and clinical partnership, Axis aims to improve outcomes in both degenerative and complex spinal procedures.
